Researchers have discovered how overactive DNA repair systems can lead to retinal damage and blindness in mice. A DNA repair enzyme called Aag glycosylase becomes hyperactive, provoking an inflammatory response that produces necrosis, leading to severe tissue damage.
Why too much DNA repair can injure tissue
Researchers have discovered how overactive DNA repair systems can lead to retinal damage and blindness in mice. A DNA repair enzyme called Aag glycosylase becomes hyperactive, provoking an inflammator..
