Fecal microbiota transplant (FMT), or the transfer of stool from a healthy donor to a patient, has been found effective in reversing severe, recurring diarrheal infections from Clostridiodes difficile in adults by restoring a normal microbiome. Now, the largest study to date of FMT in children finds the procedure to be safe and effective in eradicating an infection that is on the rise among children, even those without known risk factors.